报告人简介：

RESEARCH INTEREST：Cancer cells couldpredominantly produce energy by glycolysis even in the presence of oxygen. Thisalternative metabolic characteristic is known as the “Warburg Effect.” Althoughthe exact mechanisms underlying the Warburg effect are unclear, recent progressindicates that energy metabolism pathway of cancer cells could be a criticaltarget for drug discovery. The major research focus in my lab is todiscover anticancer compounds from traditional Chinese medicine (TCM) bytargeting cancer cells’ characteristic Warburg Effect. In order to achieve thisgoal, we are actively engaged in screening TCM for anticancer activity byinvestigating a number of onco-proteins and tumor suppressors, including thePI3K/Akt/mTOR signaling pathway, Myc, hypoxia-inducible factor and p53, whichare involved in the regulation of the metabolic adaptation.

EDUCATION

1998       Ph.D., Graduate School of NagoyaUniversity School of Medicine, Nagoya, Japan

1988        M.D., Nanjing Medical University, Nanjing, China

PROFESSIONAL EXPERIENCE

Apr2014-Current       Professor, Division ofPathology, Department of Biomedical Sciences, College of Life and HealthSciences, Chubu University, Aichi, Japan

Apr 2006- Mar2014   Associate Professor, Division of Pathology, Department ofBiomedical Sciences, College of Life and Health Sciences, Chubu University,Aichi, Japan

Oct 2001-Mar2006    Assistant Professor, Department of Biochemistry, AichiMedical University, Aichi, Japan

Apr 2000-Sep2001    Postdoctoral Fellow, National Institute for Longevity Sciences,NCGG, Japan

Apr 1998-Mar1999    Research Fellow, Department of Pathology, NagoyaUniversity School of Medicine, Nagoya, Japan

Sep 1989–Jun1993    Surgeon, the Second Affiliated Hospital of NanjingMedical University, Nanjing, China